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Statistics

Childhood Cancer Survival Rate Statistics

Doctor having a friendly talk with a mother and her daughter

About 85% of US children with cancer now survive 5 years or more. In the mid-1970s it was about 58%. By our calculation, the share of children who die within 5 years of diagnosis has fallen to about 15% from 42%, a drop of 64%.

The figure varies a great deal with the type of cancer and the child’s age. For young people diagnosed in the US between 2009 and 2015, 5-year relative survival was 99.5% for thyroid carcinoma and 59.8% for a group of brain tumors called other gliomas. Where a child lives also matters. In high-income countries 80% or more of children with cancer survive, and in low- and middle-income countries fewer than 30% do.

What Survival Looks Like for Children With Cancer Today

  • The US childhood cancer death rate fell 57% between 1975 and 2022, to 2.2 per 100,000 after 5.1 (our calculation from NCI rates).
  • Five-year survival for childhood acute lymphoblastic leukemia rose to 92.3% in 2014 to 2020, after 57% in 1975.
  • Across cancer types, 5-year survival in US children and teens spans about 40 percentage points.
  • Teens fare worse than younger children for several cancers, including lymphoid leukemia, Ewing sarcoma and rhabdomyosarcoma.
  • For every new diagnosis expected in a year, the US had about 33 survivors of childhood cancer, by our calculation.
  • WHO aims to lift global childhood cancer survival to at least 60% by 2030, double today’s rate in poorer countries.

How Childhood Cancer Survival Has Changed Since the 1970s

Five-year survival in the mid-1970s was 58% for children aged 0 to 14 and 68% for adolescents aged 15 to 19. For children diagnosed between 2013 and 2019, it ranged between 83.2% for babies under 1 and 87.8% for children aged 1 to 4. Teens aged 15 to 19 reached 87.3%.

The same climb appears in 45 years of SEER data for patients under 20. Five-year survival was 63.1% for those diagnosed in 1975 to 1979 and 85.2% for those diagnosed in 2010 to 2019. Ten-year survival rose to 82.7%, up from 58.8%.

National Cancer Institute fact sheet on cancer in children and adolescents
Screenshot: cancer.gov

Deaths fell as survival rose. The cancer death rate for Americans under 20 dropped to 2.2 per 100,000 in 2022, down from 5.1 in 1975, a 57% decline by our calculation. Even so, cancer remains the most common cause of death by disease among US children past infancy. About 1,600 children and teens die of it each year.

Childhood Cancer 5-Year Survival, Then and Now
Childhood Cancer 5-Year Survival, Then and Now. Chart: Medigencies. Source: ACS (all cancers); NCI (ALL and NHL, 1975 vs 2014-20); Sultan et al., PLoS ONE 2025 (SEER 1975-79 vs 2010-19)
MeasureEarlier periodLatest periodMedigencies calculation
5-year survival, all childhood cancersAbout 58% (mid-1970s)About 85% (now)Deaths within 5 years down 64%
5-year survival, under 20, SEER63.1% (1975 to 1979)85.2% (2010 to 2019)+22.1 points
10-year survival, under 20, SEER58.8% (1975 to 1979)82.7% (2010 to 2019)+23.9 points
Acute lymphoblastic leukemia, children57% (1975)92.3% (2014 to 2020)+35.3 points; deaths within 5 years down 82%
Non-Hodgkin lymphoma, children43% (1975)91.4% (2014 to 2020)+48.4 points; deaths within 5 years down 85%
All leukemias, under 2048.2% (1975 to 1979)85.1% (2010 to 2019)+36.9 points
All lymphomas, under 2072.9% (1975 to 1979)94.2% (2010 to 2019)+21.3 points
Cancer death rate, under 205.1 per 100,000 (1975)2.2 per 100,000 (2022)Down 57%
Source: American Cancer Society; National Cancer Institute fact sheet; Sultan et al., PLoS ONE (2025), SEER 1975 to 2019. Point changes and percentage declines calculated by Medigencies.

Parents searching after a diagnosis often land on old numbers. A children’s hospital can publish current survival figures with the period and source named, and for most families those figures are more hopeful than the ones they found first. When you use the term “5-year survival”, explain it in one sentence. Some parents read it as a limit of five years of life.

Five-Year Survival by Type of Childhood Cancer

Thyroid carcinoma had the highest 5-year relative survival among US patients under 20 diagnosed between 2009 and 2015, at 99.5%. Hodgkin lymphoma followed at 97.3% and gonadal germ cell tumors at 96.4%. At the other end, other gliomas were at 59.8%, intracranial embryonal tumors at 64.9% and rhabdomyosarcoma at 65.3%.

Five-Year Survival by Childhood Cancer Type
Five-Year Survival by Childhood Cancer Type. Chart: Medigencies. Source: NCI SEER Cancer Statistics Review 1975-2016, Table 29.6 (cases diagnosed 2009 to 2015)

The highest and lowest groups are 39.7 percentage points apart by our count. Subtype matters even within leukemia. Lymphoid leukemia reached 88.5% while acute myeloid leukemia sat at 66.0%, a 22.5-point gap inside one family of cancers.

Cancer typeAges 0 to 19Ages 0 to 14Ages 15 to 19
Thyroid carcinoma99.5%99.8%99.4%
Hodgkin lymphoma97.3%98.4%96.7%
Retinoblastoma95.7%95.7%Too few cases
Malignant melanoma94.4%94.7%94.5%
Wilms tumor and related kidney tumors92.4%92.6%Too few cases
Non-Hodgkin lymphoma89.8%90.8%88.3%
Lymphoid leukemia88.5%90.7%74.1%
Hepatoblastoma82.2%82.5%Too few cases
Astrocytoma81.2%82.8%75.4%
Neuroblastoma80.5%81.2%Too few cases
Ewing sarcoma of bone69.9%76.3%57.5%
Osteosarcoma68.0%69.0%66.6%
Acute myeloid leukemia66.0%65.9%66.3%
Rhabdomyosarcoma65.3%70.5%44.9%
Intracranial embryonal tumors64.9%64.6%67.5%
Other gliomas59.8%53.9%83.8%
All childhood cancers combined84.1%83.7%85.0%
Source: NCI SEER Cancer Statistics Review 1975 to 2016, Table 29.6, 5-year relative survival for cases diagnosed 2009 to 2015. “Too few cases” marks groups with fewer than 25 cases. Some small groups carry wider error margins.

Putting the overall 85% figure on a brain tumor page would set the wrong expectation, and a parent will notice. Give each condition page its own survival figure and period. Add a note that the child’s care team can speak to their individual outlook, and a clear path to the clinic that treats that cancer. For cancers with lower survival, give clinical trials and family support more room on the page.

How Age at Diagnosis Changes the Outlook

Lymphoid leukemia survival for children diagnosed between 2013 and 2019 was 96% at ages 1 to 4 and 94% at ages 5 to 9. It dropped to 86% at ages 10 to 14 and 78% for adolescents. Babies under 1 had the lowest figure, at 61%.

Lymphoid Leukemia Survival by Age at Diagnosis
Lymphoid Leukemia Survival by Age at Diagnosis. Chart: Medigencies. Source: National Cancer Institute, Cancer in Children and Adolescents fact sheet (2013 to 2019 data)

Sarcomas have a teen gap too. Ewing sarcoma survival was over 80% for ages 1 to 14 in 2013 to 2019, against 69% for adolescents. In the 2009 to 2015 SEER table, rhabdomyosarcoma survival was 70.5% for children under 15 and 44.9% for teens, a 25.6-point gap by our maths.

Across all cancers, teens do about as well as younger children, with 87.3% survival in 2013 to 2019. The gap appears only within particular cancers. Of the 14,910 new cancer cases expected in Americans under 20 in 2024, 5,290 were in adolescents aged 15 to 19, or 35.5% by our calculation.

Teens with cancer read the website themselves. Give them a page of their own, written in plain language for adolescents and young adults, about school and what treatment will feel like. Short videos from teen patients who choose to tell their story speak to this group directly, and each one needs a parent’s signed authorization first. Our list of healthcare social media agencies includes teams used to handling sensitive content like this. On leukemia and sarcoma pages, tell families that age affects outlook and that the care team will explain what it means for their child.

The Survival Gap Between Rich and Poor Countries

An estimated 400,000 children and adolescents aged 0 to 19 develop cancer worldwide each year. In high-income countries 80% or more survive, against fewer than 30% in low- and middle-income countries. By our calculation, a child in a high-income country is about 2.7 times as likely to survive.

World Health Organization page on improving the childhood cancer cure rate
Screenshot: who.int

WHO launched the Global Initiative for Childhood Cancer in 2018 with a target of at least 60% survival by 2030. For low- and middle-income countries, that means roughly doubling the current rate.

In CONCORD-3, the global cancer survival study covering patients diagnosed between 2000 and 2014, the size of the gap depends on the cancer. Five-year survival for childhood acute lymphoblastic leukemia was above 90% in Canada, the US and nine European countries. It stayed below 60% in China, Mexico and Ecuador. For childhood brain tumors diagnosed in 2010 to 2014, survival was below 40% in Brazil and Mexico and around 80% in Sweden, Denmark and Slovakia.

MeasureHigher-survival settingsLower-survival settingsGap
All childhood cancers80% or more (high-income countries)Under 30% (low- and middle-income countries)At least 50 points; about 2.7 times
Acute lymphoblastic leukemia, childrenOver 90% (Canada, US, nine European countries)Under 60% (China, Mexico, Ecuador)More than 30 points
Brain tumors, children, 2010 to 2014About 80% (Sweden, Denmark, Slovakia)Under 40% (Brazil, Mexico)About 40 points
Leukemia, ages 0 to 24, 2010 to 2014Over 85% (Canada, Cyprus, Belgium, Denmark, Finland, Australia)46% (Mexico)About 40 points
WHO target for 2030At least 60% survival worldwideAbout double today’s rate in poorer countries
Source: WHO Global Initiative for Childhood Cancer; CONCORD-3 (Lancet, 2018) via the London School of Hygiene and Tropical Medicine; CONCORD-3 leukaemia analysis, Lancet Child and Adolescent Health (2022). Gaps calculated by Medigencies.

A US hospital with an international patient office should spell out how to request a records review and which languages its staff speak. Leave out comparisons that suggest care in a family’s home country is hopeless. Some families from the countries in this table may already live nearby, so parent pages in Spanish and other languages matter.

Childhood Cancer Survivors and Late Effects

About 495,739 people diagnosed with cancer before age 20 were alive in the US on January 1, 2020. Against the 14,910 new cases expected in 2024, that is about 33 survivors for every new diagnosis, by our calculation.

Many survivors face serious health problems later in life. In a cohort treated between 1970 and 1986, more than half had a severe or disabling complication, or had died, by age 50. Conditional life expectancy for childhood cancer survivors is 15% to 25% lower than for their peers, and the gap is larger for people treated with radiotherapy.

A small number of deaths still occur after the 5-year mark. For patients under 20 diagnosed in 2010 to 2019, 5-year survival was 85.2% and 10-year survival 82.7%, a 2.5-point difference. Follow-up care needs to run well past year five.

About 9,680 US children aged 0 to 14 will be diagnosed with cancer in 2026. For all Americans under 20, 1,590 deaths were expected against 14,910 new cases in 2024, about 11 deaths for every 100 diagnoses in a single year by our calculation.

Survivors outnumber new patients about 33 to 1, and many are now adults who no longer see a pediatrician. Write the survivorship clinic page for adults treated as children. List the follow-up checks the clinic offers and say how to book without a pediatric referral. Pages on going back to school and returning to sport keep families in touch with the program for years.

How Pediatric Oncology Programs Can Communicate Survival Data Ethically

More than 220 children’s hospitals, universities and cancer centers belong to the Children’s Oncology Group. Its member institutions care for more than 80% of US children and adolescents diagnosed with cancer, and most children treated at these centers take part in a clinical trial. Parents are encouraged to ask about trials and to consider a second opinion.

American Cancer Society page on finding treatment for childhood cancer
Screenshot: cancer.org

Put clinical trials near the top of a pediatric oncology site. The trials page should list open studies by cancer type and age, with a named contact. Say in plain words what taking part involves for a child and family. Our oncology marketing agencies and pediatrics marketing agencies include teams that build this kind of content.

St. Jude Children’s Research Hospital publishes a school program guide for parents that explains how children keep up with schoolwork during treatment. A hospital without its own school program can still write a page on how teachers and the care team share updates.

St. Jude Children's Research Hospital school program page for parents
Screenshot: stjude.org

Under the HIPAA Privacy Rule, a covered entity generally needs a person’s written authorization before using their protected health information for marketing. For a child, that means a signed authorization from a parent or guardian before any story, photo or video runs. A story describing an outcome better than most families can expect also needs the generally expected result alongside it, under FTC endorsement guidance.

Google treats health conditions as a sensitive category for personalized ads. Customer Match, your data segments and lookalike segments are off the table for these campaigns. The details are in our guide to Google’s healthcare ad rules, and programmatic advertising in healthcare explains the limits on display buying.

Google Ads policy page on health as a sensitive category in personalized advertising
Screenshot: support.google.com
TopicWrite it this wayAvoid
Survival figures“For children diagnosed with ALL in 2014 to 2020, 5-year survival was 92.3%.”“Over 90% cured” or a single figure for every cancer
Hope and outcomesCurrent data, the period, and a note that the care team will explain each child’s outlookFear lines such as “Every minute counts” in ads
Patient storiesSigned parent or guardian authorization; the family’s own wordsStories that imply every child will have the same result
Clinical trialsOpen trials by type and age, a named contact, plain-language consent stepsCalling a trial a “breakthrough cure”
FundraisingSeparate pages and appeals from care informationMixing donation asks into treatment pages
SurvivorsLong-term follow-up clinic pages for adults treated as childrenEnding the story at the last day of treatment
Source: Medigencies communication guide built from NCI, SEER, HHS HIPAA marketing guidance, FTC endorsement guidance and Google Ads policy pages.

Let families describe the illness in their own words. Hospital copy should leave out battle language unless a family uses it in its own story. Count second-opinion inquiries and trial referrals, which tell you whether the content reaches parents at the right moment. Hospitals that want outside support can compare hospital and health system marketing agencies with specialist healthcare content marketing agencies. Our list of healthcare reputation management agencies covers review and story programs. Our editorial policy explains how we handle health data.

Questions Parents Ask About Childhood Cancer Survival

What Is the Survival Rate for Childhood Cancer?

About 85% of US children with cancer survive 5 years or more. For those diagnosed between 2013 and 2019, 5-year survival by age band ranged between 83.2% and 87.8%.

Which Childhood Cancer Has the Highest Survival Rate?

Thyroid carcinoma had 99.5% 5-year relative survival in US patients under 20 diagnosed between 2009 and 2015. Hodgkin lymphoma was at 97.3% and retinoblastoma at 95.7%.

Which Childhood Cancers Have Lower Survival Rates?

Some brain tumors, sarcomas and acute myeloid leukemia had 5-year survival in the 60% range or below for 2009 to 2015. Other gliomas were lowest at 59.8%.

How Much Has Childhood Cancer Survival Improved?

Five-year survival is now about 85%, up from about 58% in the mid-1970s. The death rate for Americans under 20 fell 57% between 1975 and 2022.

Do Teenagers Have Lower Survival Than Younger Children?

For some cancers, yes. Lymphoid leukemia survival was 78% for adolescents against 96% for children aged 1 to 4 in 2013 to 2019. Across all cancers combined, survival for teens is similar to that of younger children.

SEER Tables, NCI and WHO Pages Used for These Survival Figures

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